Melon + Other Fruits: Why This Combination Can Upset Digestion Melon + Other Fruits: Why This Combination Can Upset Digestion Melons are refreshing, hydrating, and delicious—but they come with one special rule: “Eat melon alone or leave it alone.” This traditional nutrition principle exists for a reason. When melon is eaten together with other fruits like grapes or bananas, many people experience bloating, indigestion, or discomfort. Why Melon Doesn't Mix Well Melon digests very quickly—faster than most fruits. When you combine melon with slower-digesting fruits such as grapes or bananas , it tends to ferment in the stomach, leading to gas or bloating. The Digestion Speed Mismatch Melon : high water content, breaks down rapidly. Grapes & bananas : contain more fiber, sugar, and starch, which slows digestion. When these are eaten together, the melon may stay longer in the stomach than intended, causing discomfort for s...